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Histological analysis of the intestinal wall of newborn rats submitted to hypoxia and reoxygenation to evaluate the protective effect of N-Acetylcysteine.

Soraia Guerra SilvaresAntonio Fernandes MoronManuel de Jesus SimõesÁlvaro Ulhoa CintraEdna Frasson de Souza MonteroAntonio Fernandes MoronJosé Luiz Martins
Published in: Acta cirurgica brasileira (2020)
The administration of NAC decreased the lesions in the intestinal wall of rats submitted to H/R, therefore suggesting that this drug can be used to prevent the development of necrotizing enterocolitis in newborns.
Keyphrases
  • low birth weight
  • transcription factor
  • pregnant women
  • endothelial cells
  • emergency department
  • induced apoptosis
  • preterm infants
  • signaling pathway
  • oxidative stress
  • adverse drug