FLP-catalysis meets hydrogen-bond activation.
Nikolai A SitteLaura KöringPeter W RoeskyJan ParadiesPublished in: Organic & biomolecular chemistry (2022)
The potential of two chiral amidines and three non-chiral boranes in the metal-free hydrogen activation was explored. The resulting chiral amidiunium borohydride salts were investigated in asymmetric hydrogenation reactions of ketimines, activated double bonds and dehydro amioacid esters.