Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour.

Published in: Pharmaceutical research (2022)

Tissue hydraulic permeability as an intrinsic property can influence drug accumulation and distribution. Results from this study can deepen the understanding of the interplays between drug and tissues that are involved in the drug delivery processes in chemotherapy.

Keyphrases

drug delivery
locally advanced
endothelial cells
gene expression
white matter
cancer therapy
resting state
radiation therapy
brain injury
iron oxide