Exploring the Utility of a Functional Magnetic Resonance Imaging (fMRI) Cannabis Cue-Reactivity Paradigm in Treatment Seeking Adults with Cannabis Use Disorder.

Gregory L Sahlem Logan T Dowdle Nathaniel L BakerBrian J ShermanKevin M GrayAimee L McRae-ClarkBrett FroeligerLindsay M Squeglia

Published in: medRxiv : the preprint server for health sciences (2023)

We found that, among two separate treatment-seeking CUD groups, cannabis cue-reactivity was evidenced by greater activation and tbFC in regions related to executive function and reward processing, and craving was negatively associated with cue-reactivity in the ventral striatum. Future directions include examining if pharmacological, neuromodulatory, or psychosocial interventions can alter corticostriatal cue-reactivity.

Keyphrases

magnetic resonance imaging
mental health
physical activity
combination therapy
magnetic resonance
contrast enhanced
replacement therapy