Evaluation of [18F]CP18 as a Substrate-Based Apoptosis Imaging Agent for the Assessment of Early Treatment Response in Oncology.
Sara RapicChristel VangestelFilipe ElvasJeroen VerhaegheTim Van den WyngaertLeonie WyffelsPatrick PauwelsSteven StaelensSigrid StroobantsPublished in: Molecular imaging and biology (2018)
Both our in vitro and in vivo findings have shown the ability of [18F]CP18-PET to visualize therapy-induced cancer cell apoptosis and possibly serve as a biomarker for early therapy response.