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Exhaled nitric oxide in ethnically diverse high-altitude native populations: A comparative study.

Sudipta GhoshMelisa KiyamuPaloma ContrerasFabiola León-VelardeAbigail BighamTom D Brutsaert
Published in: American journal of physical anthropology (2019)
In contrast to previous work, we found lower PENO in populations at altitude (compared to sea-level) and no difference in PENO between Tibetan and Andean highland native populations. These results do not support the hypothesis that high nitric oxide in human lungs is a universal adaptive mechanism of highland native populations to offset hypobaric hypoxia.
Keyphrases
  • nitric oxide
  • endothelial cells
  • genetic diversity
  • hydrogen peroxide
  • magnetic resonance
  • nitric oxide synthase
  • magnetic resonance imaging
  • computed tomography