Transcriptomic and functional analyses reveal a tumour-promoting role for the IL-36 receptor in colon cancer and crosstalk between IL-36 signalling and the IL-17/ IL-23 axis.

Kevin James BakerElizabeth Brint Aileen Houston

Published in: British journal of cancer (2022)

Collectively, this data support a pro-tumorigenic role for IL-36 signalling in colon cancer, with the IL-17/IL-23 axis influential in IL-36-mediated colon tumorigenesis.

Keyphrases

gene expression
single cell
genome wide
artificial intelligence
big data