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Effective neutralization of chemical warfare agents (HD, VX) by Me-DABCOF: a small molecule with dual action.

Naama Karton-LifshinShahaf KatalanIshay ColumbusRavit ChenLea YehezkelMoran MadmonShai DaganShlomi EliasGil FridkinYossi Zafrani
Published in: Chemical communications (Cambridge, England) (2019)
The ability of mono N-methyl-1,4-diazabicyclo[2.2.2]octane fluoride (Me-DABCOF, 1) to act as a bifunctional reagent that effectively and universally neutralizes both the persistent and extremely toxic blister agent HD and the nerve agent VX in nearly neutral aqueous solution, alumina powder or a hydrogel formulation, is described.
Keyphrases
  • aqueous solution
  • small molecule
  • drug delivery
  • drinking water
  • protein protein
  • hyaluronic acid
  • highly efficient
  • wound healing