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Utility of Homologous Recombination Deficiency Biomarkers Across Cancer Types.

Shiro TakamatsuJ B BrownKen YamaguchiJunzo HamanishiKoji YamanoiHisamitsu TakayaTomoko KaneyasuSeiichi MoriMasaki MandaiNoriomi Matsumura
Published in: JCO precision oncology (2021)
This study provides evidence for the usefulness of HRD analysis in all cancer types, improves chemotherapy decision making and its efficacy in clinical settings, and represents a substantial advancement in precision oncology.A comprehensive pan-cancer analysis on the clinical significance of homologous recombination deficiency.
Keyphrases
  • papillary thyroid
  • dna repair
  • dna damage
  • squamous cell
  • decision making
  • palliative care
  • squamous cell carcinoma
  • lymph node metastasis
  • childhood cancer
  • locally advanced