Utility of Homologous Recombination Deficiency Biomarkers Across Cancer Types.
Shiro TakamatsuJ B BrownKen YamaguchiJunzo HamanishiKoji YamanoiHisamitsu TakayaTomoko KaneyasuSeiichi MoriMasaki MandaiNoriomi MatsumuraPublished in: JCO precision oncology (2021)
This study provides evidence for the usefulness of HRD analysis in all cancer types, improves chemotherapy decision making and its efficacy in clinical settings, and represents a substantial advancement in precision oncology.A comprehensive pan-cancer analysis on the clinical significance of homologous recombination deficiency.