Improving high-resolution copy number variation analysis from next generation sequencing using unique molecular identifiers.
Pierre-Julien ViaillyVincent SaterMathieu ViennotElodie BohersNicolas VergneCaroline BerardHélène DauchelThierry LecroqAlison CelebiPhilippe RuminyVinciane MarchandMarie-Delphine LanicSydney DuboisDominique PentherHervé TillySylvain MareschalFabrice JardinPublished in: BMC bioinformatics (2021)
We provide mCNA, a new approach for CNV detection, freely available at https://gitlab.com/pierrejulien.viailly/mcna/ under MIT license. mCNA can significantly improve detection accuracy of CNV changes by using UMI.