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Phospho-Tyr705 of STAT3 is a therapeutic target for sepsis through regulating inflammation and coagulation.

Shunyao XuXiaojun PanLingjie MaoHao PanWenwei XuYufeng HuXueshu YuZhiqiang ChenSongzan QianYincai YeYueyue HuangJingye Pan
Published in: Cell communication and signaling : CCS (2020)
Our results revealed a therapeutic role of pY-STAT3 in modulating the inflammatory response and defective coagulation during sepsis. Video Abstract.
Keyphrases
  • inflammatory response
  • septic shock
  • acute kidney injury
  • intensive care unit
  • cell proliferation
  • oxidative stress
  • lipopolysaccharide induced
  • signaling pathway
  • single cell
  • lps induced