Efficacy and Safety of Dupilumab Versus Omalizumab in Chronic Rhinosinusitis With Nasal Polyps and Asthma: EVEREST Trial Design.
Lucia De Prado Gomez PharmD MScAsif H Khan Mbbs MphAnju T Peters MdClaus Bachert Md PhDMartin WagenmannEnrico Heffler Md PhDClaire Hopkins BMBChPeter W Hellings Md PhDMei Zhang PhDJun Xing PhDPaul Rowe MdJuby A Jacob-Nara Md Mph DHScPublished in: American journal of rhinology & allergy (2022)
EVEREST is the first head-to-head trial assessing the comparative efficacy and safety of 2 biologics in patients with severe CRSwNP and comorbid asthma. The study will provide evidence to help optimize treatment plans for patients that suffer from severe CRSwNP and comorbid asthma.
Keyphrases
- chronic rhinosinusitis
- chronic obstructive pulmonary disease
- lung function
- end stage renal disease
- allergic rhinitis
- study protocol
- phase iii
- clinical trial
- ejection fraction
- chronic kidney disease
- newly diagnosed
- early onset
- phase ii
- optic nerve
- peritoneal dialysis
- prognostic factors
- patient reported outcomes
- health insurance