Effects of choline supplementation in mothers with hypothyroidism on the brain-derived neurotrophic factor gene expression changes in pre-pubertal offspring rats.

Siamak SheikhiLeila DerafshpourRazieh AghazadehHojat SayyadiEhsan SabooryMorteza Bagheri

Published in: Molecular biology reports (2022)

It can be concluded that maternal choline supplementation on the first day of gestation until PND 21 improves brain development and cognitive function in pre-pubertal offspring rats regarding control/hypothyroidism groups.

Keyphrases

gene expression
high fat diet
replacement therapy
preterm infants
dna methylation
resting state
white matter
birth weight
gestational age
type diabetes
pregnancy outcomes
pregnant women
functional connectivity
cerebral ischemia
physical activity
blood brain barrier
brain injury
weight loss
smoking cessation