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The relative importance of predictive factors for single first-generation EGFR-TKI use for more than 5 years in patients with advanced non-small cell lung cancer: Taiwan multicenter TIPS-5 study.

Yen-Hsiang HuangJen-Yu HungHow-Wen KoPo-Lan SuChun-Liang LaiHuang-Chih ChangTe-Chun HsiaSheng-Hao LinKuan-Li WuCheng-Ta YangWu-Chou SuYi-Chun ChuChin-Chou WangWei-Yu LiaoYen-Ting LinChing-Hsiung LinMeng-Chih LinKuo-Hsuan HsuJeng-Sen TsengTsung-Ying YangKun-Chieh ChenMei-Hsuan LeeSung-Liang YuChao-Chi HoGee-Chen Chang
Published in: Therapeutic advances in medical oncology (2021)
For NSCLC patients with single first-generation EGFR-TKI use for ⩾5 Y, factors with different relative importance exist and the risk-scoring model is feasible with modest accuracy. The role of local treatment for primary tumors in patients with long-term TKI use requires further investigation.
Keyphrases
  • advanced non small cell lung cancer
  • epidermal growth factor receptor
  • tyrosine kinase
  • small cell lung cancer
  • double blind
  • clinical trial
  • smoking cessation
  • breast cancer risk