Effect of Contact Lens Solutions in Stabilizing the Activity of Tear Lysozyme.
Catherine A ScheuerVicki L BarniakNitasha R PhatakMarjorie J RahWilliam ReindelPublished in: Clinical optometry (2023)
The representative tear protein lysozyme was significantly more stable in the novel kalifilcon A contact lens solution containing multiple moisturizers and osmoprotectants than in PBS or other daily disposable contact lens solutions. The lysozyme activity assay provides mechanistic evidence that the kalifilcon A contact lens solution can stabilize proteins under conditions that typically denature proteins, which may contribute to maintaining ocular surface homeostasis.