Germline Testing and Somatic Tumor Testing for <i>BRCA1/2</i> Pathogenic Variants in Ovarian Cancer: What Is the Optimal Sequence of Testing?

Janice S KwonSarah A CookJennifer SantosKatie ComptonSophie Sun Kasmintan A Schrader Aly Karsan

Published in: JCO precision oncology (2022)

The ASCO strategy may identify more <i>BRCA</i> PVs but is not cost-effective. Tumor testing in epithelial ovarian cancer as triage for germline testing is the favored strategy in this health care system.

Keyphrases

emergency department
dna repair
copy number
gene expression
dna damage