Cholesterol functionalized aliphatic N-substituted 8-membered cyclic carbonate.

Shrinivas Venkataraman Kenneth P Mineart Vivek M Prabhu James L Hedrick Yi Yan Yang

Published in: Polymer chemistry (2018)

Straightforward synthesis of cholesterol functionalized aliphatic N-substituted 8-membered cyclic carbonate (Chol-8m) monomer is reported. Well-defined poly(ethylene glycol) (PEG) diblock copolymers were readily accessed via organo catalytic ring opening polymerization. These polymers show promise as building blocks for self-assembled nanostructures and steric stabilizers for liposomes.

Keyphrases

molecularly imprinted
low density lipoprotein
molecular docking
drug delivery
quantum dots
drug release
molecular dynamics simulations
machine learning
artificial intelligence
deep learning