Newly diagnosed glioblastoma in geriatric (65 +) patients: impact of patients frailty, comorbidity burden and obesity on overall survival.

Matthias SchneiderAnna-Laura PotthoffElisa ScharnböckMuriel HeimannNiklas SchäferJohannes WellerChristina SchaubAndreas H JacobsErdem GüresirUlrich HerrlingerHartmut VatterPatrick Schuss

Published in: Journal of neuro-oncology (2020)

The present study concludes that both increased frailty and comorbidity burden are significantly associated with poor OS in geriatric patients with glioblastoma. Further, the present series suggests an obesity paradox in geriatric glioblastoma patients.

Keyphrases

newly diagnosed
end stage renal disease
ejection fraction
chronic kidney disease
metabolic syndrome
type diabetes
peritoneal dialysis
prognostic factors
adipose tissue
patient reported outcomes
skeletal muscle
body mass index
risk factors
high fat diet induced