Prognostic Genomic Markers of Pathological Stage in Oral Squamous Cell Carcinoma.
Su Kyung KukJae Il LeeKi Tae KimPublished in: Head and neck pathology (2022)
The genetic mutation type and ratio of tumor heterogeneity are different for each stage of OSCC, and stratification of OSCC patients with differential therapeutic efficacy is needed. Risk genes of both high and low stages must be identified in patients diagnosed with low-stage OSCC. Mutations in NOMO1, ZNF333, and WIZ should be considered as potential prognostic markers.