Technical note: hydrogel-based mimics of prostate cancer with matched relaxation, diffusion and kurtosis for validating multi-parametric MRI.

Dariya I MalyarenkoShigeto OnoTed J E LynchScott D Swanson

Published in: Medical physics (2023)

A stable biomimetic mpMR reference based on hydrogels has been developed with a range of multi-compartment diffusion and relaxation parameter combinations observed in cancerous and healthy prostate tissue.

Keyphrases

prostate cancer
tissue engineering
drug delivery
radical prostatectomy
hyaluronic acid
diffusion weighted imaging
single molecule
magnetic resonance imaging
contrast enhanced
drug release
benign prostatic hyperplasia