Anti-Ro/SSA and/or anti-La/SSB antibodies are associated with adverse endometrial status.
Fangting LuYanshi WangXuhui FangRentao JinBo XuQiannan QiuLi WuPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2022)
Menstrual blood cell composition differs between anti-SSA/SSB antibody-positive women and normal controls, especially in terms of CD49a+ NK cells and CD8+T cells, unbalancing the immune cell composition and inflammatory uterine microenvironment and possibly contributing to adverse pregnancy outcomes.