Genetic polymorphisms in genes regulating cell death and prognosis of patients with rectal cancer receiving postoperative chemoradiotherapy.
Hongxia ChenLuxi YinJie YangNingxin RenJinna ChenQixuan LuYing HuangYanru FengWeihu WangShulian WangYueping LiuYongwen SongYexiong LiJing JinWen TanDongxin LinPublished in: Cancer biology & medicine (2023)
Polymorphisms in genes regulating cell death may play essential roles in the prognosis of patients with rectal cancer who are treated with postoperative CRT and may serve as potential genetic biomarkers for individualized treatment.
Keyphrases
- rectal cancer
- cell death
- locally advanced
- genome wide
- patients undergoing
- cell cycle arrest
- genome wide identification
- dna methylation
- squamous cell carcinoma
- genome wide analysis
- combination therapy
- radiation therapy
- copy number
- cardiac resynchronization therapy
- signaling pathway
- climate change
- left ventricular
- newly diagnosed
- risk assessment
- gene expression