EANM position paper on challenges and opportunities of full-ring 360° CZT bone imaging: it's time to let go of planar whole-body bone imaging.
Richard GrahamDavid MorlandSarah CadeLaetitia ImbertEmmanouil PanagiotidisJens KurthFrédéric PaychaTim Van den WyngaertPublished in: European journal of nuclear medicine and molecular imaging (2024)
The introduction of smaller footprint, more sensitive Cadmium-Zinc-Telluride (CZT)-based detectors with improved spatial and energy resolution has enabled the design of innovative full-ring 360° CZT SPECT/CT systems (e.g., VERITON ® and StarGuide™). With this transformative technology now aiming to become mainstream in clinical practice, several critical questions need to be addressed. This EANM position paper provides practical recommendations on how to use these devices for routine bone SPECT/CT studies, facilitating the transition from traditional planar whole-body imaging and conventional SPECT/CT to these novel systems. In particular, initial guidance is provided on imaging acquisition and reporting workflows, image reconstruction, and CT acquisition parameters. Given the emerging nature of this technology, the available evidence base is still limited, and the proposed adaptations in workflows and scan protocols will likely evolve before being integrated into definitive guidelines. In the meantime, this EANM position paper serves as a comprehensive guide for integrating these advanced hybrid SPECT/CT imaging systems into clinical practice and outlining areas for further study.
Keyphrases
- clinical practice
- high resolution
- computed tomography
- dual energy
- image quality
- contrast enhanced
- bone mineral density
- positron emission tomography
- pet ct
- emergency department
- machine learning
- squamous cell carcinoma
- risk assessment
- postmenopausal women
- heavy metals
- high intensity
- deep learning
- magnetic resonance
- bone regeneration
- photodynamic therapy
- single molecule
- locally advanced
- oxide nanoparticles