Regulation of Immunity in Clear Cell Renal Carcinoma: Role of PD-1, PD-L1, and PD-L2.

Liudmila V SpirinaZahar YurmazovEvgeny UsyninIrina KondakovaEkaterine LadutkoEvgeny Choynzonov

Published in: Current issues in molecular biology (2021)

We present a new instrument targeting pathologies with p-VHL/HIF altered function that impact the PD-L2 expression through the change in transcriptional, growth factors, and AKT/mTOR modulation.

Keyphrases

clear cell
cell proliferation
signaling pathway
gene expression
transcription factor
cancer therapy
endothelial cells
patient reported outcomes
heat shock
oxidative stress