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My 60-Year Love Affair with Natural Products.

David G I Kingston
Published in: Journal of natural products (2021)
The author describes his 60-year career in studying the chemistry of natural products, which includes structural, synthetic, and biosynthetic studies of natural products ranging from insect pigments, antibiotics, and fecal mutagens to taxol and other anticancer natural products as well as antimalarial natural products. One of the compounds discussed, napabucasin, is now an anticancer drug in phase III clinical trials.
Keyphrases
  • phase iii
  • clinical trial
  • open label
  • phase ii
  • double blind
  • placebo controlled
  • study protocol
  • drug discovery
  • case control
  • aedes aegypti