Risk and impact of delayed renal impairment in patients with locally advanced head and neck squamous cell carcinoma receiving chemoradiotherapy with cisplatin.
Thana PatimarattanananArkom NongnuchPoompis PattaranutapornNattawut UnwanathamChuleeporn JiarpinitnunNuttapong NgamphaiboonPublished in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2020)
Almost one third of LA-HNSCC patients who underwent CRT with cisplatin developed AKD, and their eGFR did not recover to baseline even after 1 year. ECOG 0 and hypertension were associated with AKD. These findings may have been due to the physician's awareness of AKD and underestimation of its potential complications in fit patients.
Keyphrases
- end stage renal disease
- locally advanced
- ejection fraction
- newly diagnosed
- blood pressure
- squamous cell carcinoma
- rectal cancer
- emergency department
- prognostic factors
- small cell lung cancer
- peritoneal dialysis
- primary care
- radiation therapy
- risk factors
- heart failure
- epidermal growth factor receptor
- patient reported outcomes
- lymph node
- atrial fibrillation
- patient reported
- study protocol
- phase ii study
- double blind