Lymphatic filariasis epidemiology in Samoa in 2018: Geographic clustering and higher antigen prevalence in older age groups.

Colleen L Lau Kelley Meder Helen J Mayfield Therese M KearnsBrady McPhersonTake NaseriRobert ThomsenShannon M HedtkeSarah SheridanKatherine GassPatricia M Graves

Published in: PLoS neglected tropical diseases (2020)

Our study confirmed ongoing transmission of LF in Samoa, in accordance with the 2017 TAS results. Ag prevalence varied significantly between PSUs, and there was poor correlation between prevalence in 5-9 year-olds and older ages, who had threefold higher prevalence. Sampling older age groups would provide more accurate estimates of overall prevalence, and be more sensitive for identifying residual hotspots. Higher prevalence in purposively selected PSUs shows local knowledge can help identify at least some hotspots.

Keyphrases

risk factors
healthcare
physical activity
middle aged
community dwelling
single cell
rna seq