Immunophenotype of neutrophils in oral squamous cell carcinoma patients.
Patrícia Carlos CaldeiraÉrica Leandro Marciano VieiraAlexandre Andrade SousaAntônio Lúcio TeixeiraMaria Cássia Ferreira AguiarPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2017)
The amount and immunophenotype of neutrophils and lymphocytes differ between patients and healthy individuals, with a pro-tumorigenic profile of neutrophils. As these cells also get within tumor microenvironment, they possibly exert systemic and local functions in cancer pathogenesis. The association of neutrophil count with outcome corroborates recent studies and this merits further investigation for applicability as a prognosticator.