Vaccine-induced gastric CD4+ tissue-resident memory T cells proliferate in situ to amplify immune response against Helicobacter pylori insult.

Ningyin XuGuojing RuanWei LiuChupeng HuAn HuangZhiqin ZengShuanghui LuoZhenxing ZhangMenghui FanFeng YeTao Xi Yingying Xing

Published in: Helicobacter (2019)

Our study reveals that H pylori vaccine-induced CD4+ TRM cells can proliferate and differentiate in situ to enhance gastric local immunity during recall response.

Keyphrases

helicobacter pylori
immune response
high glucose
diabetic rats
induced apoptosis
helicobacter pylori infection
patient safety
working memory
cell cycle arrest
dendritic cells
signaling pathway
inflammatory response
endoplasmic reticulum stress