Preventive effect of Rumex crispus L. on surgically induced intra-abdominal adhesion model in rats.
Ipek SuntarMurside Ayse DemirelAli Osman CeribasiIrem ErginAlper GökbulutPublished in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2021)
Adhesion scores, inflammatory cytokines and inflammation cells decreased by the application of R. crispus root extract. The fractions also showed similar anti-inflammatory effects, but R60 was found to be more effective in prevention of intra-abdominal adhesions and uterine fibrosis. R60 fraction, possessing potential bioactivity, was investigated in terms of phenolic composition by HPLC.
Keyphrases
- oxidative stress
- induced apoptosis
- diabetic rats
- ms ms
- biofilm formation
- cell cycle arrest
- high glucose
- simultaneous determination
- cell migration
- high performance liquid chromatography
- cell death
- drug induced
- human health
- solid phase extraction
- pseudomonas aeruginosa
- escherichia coli
- cell proliferation
- risk assessment