Functional signaling and gene regulatory networks between the oocyte and the surrounding cumulus cells.

Published in: BMC genomics (2018)

Our analyses revealed a complex and functional gene regulatory circuit between the oocyte and surrounding cumulus cells. The regulatory profile of each cumulus-oocyte complex is likely associated with the oocytes' developmental potential to derive an embryo.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
signaling pathway
transcription factor
single cell
cell proliferation
human health