Ex vivo T-cell depletion vs post-transplant cyclophosphamide, sirolimus, and mycophenolate mofetil as graft-vs-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation.

Juan Montoro GómezElisa RoldánJosé Luis PiñanaPere BarbaPedro ChorãoAbdiel QuinteroRafael HernaniGuillermo OrtíJosé Ignacio LorenzoAitana Balaguer-RosellóOlga SalameroLaura FoxPilar SolvesInés GómezManuel GuerreiroJuan Carlos Hernández BoludaGuillermo SanzCarlos SolanoMiguel Ángel SanzDavid ValcárcelJaime Sanz

Published in: European journal of haematology (2020)

PTCy-Sir-MMF provides better survival outcomes but is associated with higher risk of cGVHD compared to TCD.

Keyphrases

allogeneic hematopoietic stem cell transplantation
acute myeloid leukemia

acute lymphoblastic leukemia

low dose

high dose