Leptin promoter methylation in female patients with painful multisomatoform disorder and chronic widespread pain.

Johannes AchenbachMathias RheinAlexander GlahnHelge FrielingMatthias Karst

Published in: Clinical epigenetics (2022)

Our findings support the hypothesis that epigenetic regulation of leptin plays a role in the regulation of leptin levels in patients with MSD. This effect is more pronounced in patients with chronic widespread pain.

Keyphrases

chronic pain
pain management
dna methylation
neuropathic pain
gene expression
genome wide
transcription factor
spinal cord injury
spinal cord