Genetic Mechanism Study of Auditory Phoenix Spheres and Transcription Factors Prediction for Direct Reprogramming by Bioinformatics.

Published in: International journal of molecular sciences (2022)

Ten hub genes were identified to be the key candidates for self-renewal. Ten TFs were predicted as the direct reprogramming factors. This study provides a theoretical foundation for understanding phoenix cells and clues for direct reprogramming, which would stimulate further experiments and clinical applications in hearing research and treatment.

Keyphrases

transcription factor
genome wide
induced apoptosis
cell death
cell cycle arrest
signaling pathway
copy number
smoking cessation