Pharmacokinetic-guided prophylaxis improved clinical outcomes in paediatric patients with severe haemophilia A.

Huang KunYingzi ZhenGang LiXinyi WuZhenping ChenRunhui Wu

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2021)

PK-guided prophylaxis can help haemophiliac patients improve quality of life by decreasing bleeds with appropriate FVIII consumption and reducing infusion frequency without increments in bleeds, thus optimizing haemophilia treatment.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
intensive care unit
emergency department
low dose
prognostic factors
early onset
patient reported outcomes
combination therapy
drug induced