Functional Connectivity and Structural Disruption in the Default-Mode Network Predicts Cognitive Rehabilitation Outcomes in Multiple Sclerosis.
Tom A FuchsStefano ZiccardiRalph H B BenedictAlexander BartnikAmy KuceyeskiLeigh E CharvetDevon OshipBianca Weinstock-GuttmanCurtis WojcikDavid HojnackiChanna KolbJose EscobarRebecca CampbellHoan Duc TranNiels P BergslandDejan JakimovskiRobert ZivadinovMichael G DwyerPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2020)
Patient response to restorative cognitive rehabilitation is predictable from the interaction between structural network disruption and functional connectivity in the default-mode network. This effect may be related to cognitive reserve.