Drug-free in vitro activation combined with 3D-bioprinted adipose-derived stem cells restores ovarian function of rats with premature ovarian insufficiency.
Qian LiJiahua ZhengZhongkang LiYanlai XiaoMingle ZhangWenxin ShiHe GaoXiang-Hua HuangJingkun ZhangPublished in: Stem cell research & therapy (2022)
Our results suggested that 3D-bioprinted engineering ovary had great potential for restoring impaired ovarian function of rats with POI, which could compensate for the disadvantages of drug-free IVA to some extent.