Effect of tetrahedral DNA nanostructures on proliferation and osteogenic differentiation of human periodontal ligament stem cells.
Mi ZhouNanxin LiuQi ZhangTaoran TianQuanquan MaTao ZhangXiaoxiao CaiPublished in: Cell proliferation (2019)
Tetrahedral DNA nanostructure treatment facilitated the proliferation of PDLSCs, significantly promoted osteogenic differentiation by regulating the Wnt/β-catenin signalling pathway. Therefore, TDNs could be a novel nanomaterial with great potential for application to PDLSC-based bone tissue engineering.
Keyphrases
- stem cells
- tissue engineering
- circulating tumor
- signaling pathway
- cell free
- cell proliferation
- single molecule
- endothelial cells
- mesenchymal stem cells
- bone marrow
- epithelial mesenchymal transition
- induced pluripotent stem cells
- soft tissue
- circulating tumor cells
- combination therapy
- human health
- smoking cessation
- bone regeneration