Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer.
Balraj SinghParminder KaurSachin GuptaNirmal GuragaiMichael MaroulesPublished in: Journal of investigative medicine high impact case reports (2021)
Bladder cancer is the most common urinary tract malignancy. Platinum-based chemotherapy is the first line of treatment in locally advanced or metastatic bladder cancer. Immunotherapy has become a novel therapy option in a broad variety of malignancies including bladder cancer. Immunotherapy is approved as first line of treatment in patients who are ineligible for platinum-based chemotherapy and second-line treatment for metastatic urothelial cancer who progressed after platinum-based treatments. We present the case of an 83-year-old female with metastatic bladder cancer who was chemotherapy ineligible and had complete response with immune checkpoint inhibitor pembrolizumab.
Keyphrases
- locally advanced
- squamous cell carcinoma
- small cell lung cancer
- urinary tract
- rectal cancer
- neoadjuvant chemotherapy
- radiation therapy
- phase ii study
- papillary thyroid
- combination therapy
- bone marrow
- high grade
- muscle invasive bladder cancer
- lymph node metastasis
- squamous cell
- lymph node
- mesenchymal stem cells
- epidermal growth factor receptor
- tyrosine kinase