Dynamic Arterial Elastance as a Predictor of Supine-to-Prone Hypotension (SuProne Study): An Observational Study.

Background and Objectives : Supine-to-prone hypotension is caused by increased intrathoracic pressure and decreased venous return in the prone position. Dynamic arterial elastance (Ea dyn ) indicates fluid responsiveness and can be used to predict hypotension. This study aimed to investigate whether Ea dyn can predict supine-to-prone hypotension. Materials and Methods : In this prospective, observational study, 47 patients who underwent elective spine surgery in the prone position were enrolled. Supine-to-prone hypotension is defined as a decrease in Mean Arterial Pressure (MAP) by more than 20% in the prone position compared to the supine position. Hemodynamic parameters, including systolic blood pressure (SAP), diastolic blood pressure, MAP, stroke volume variation (SVV), pulse pressure variation (PPV), stroke volume index, cardiac index, dP/dt, and hypotension prediction index (HPI), were collected in the supine and prone positions. Supine-to-prone hypotension was also assessed using two different definitions: MAP prone < 65 mmHg and SAP prone < 100 mmHg. Hemodynamic parameters were analyzed to determine the predictability of supine-to-prone hypotension. Results : Supine-to-prone hypotension occurred in 13 (27.7%) patients. Ea dyn did not predict supine-to-prone hypotension [Area under the curve (AUC), 0.569; p = 0.440]. SAP supine > 139 mmHg (AUC, 0.760; p = 0.003) and dP/dt supine > 981 mmHg/s (AUC, 0.765; p = 0.002) predicted supine-to-prone hypotension. MAP supine , SAP supine , PPV supine , and HPI supine predicted MAP prone <65 mm Hg. MAP supine , SAP supine , SVV supine , PPV supine , and HPI supine predicted SAP prone < 100 mm Hg. Conclusions : Dynamic arterial elastance did not predict supine-to-prone hypotension in patients undergoing spine surgery. Systolic arterial pressure > 139 mmHg and dP/dt > 981 mmHg/s in the supine position were predictors for supine-to-prone hypotension. When different definitions were employed (mean arterial pressure < 65 mmHg in the prone position or systolic arterial pressure < 100 mmHg in the prone position), low blood pressures in the supine position were related to supine-to-prone hypotension.