Long-Term Risk of Ovarian Cancer and Borderline Tumors After Assisted Reproductive Technology.
Mandy SpaanAlexandra W van den Belt-DuseboutCornelis Nils LambalkHester H van BovenRoel SchatsMarian KortmanFrank J M BroekmansJoop S E LavenEvert J P van SantbrinkDidi D M BraatLucette A J van der WesterlakenBen J CohlenAstrid E P CantineauJesper M J SmeenkMinouche M van RumsteMariëtte GoddijnRon J T van GoldePaul A M MeeuwissenCarl J C M HamiltonGabriële M OuwensMiranda A GerritsmaMichael SchaapveldCurt W BurgerFlora E van LeeuwenPublished in: Journal of the National Cancer Institute (2022)
Increased ovarian cancer risk in ART-treated women compared with the general population is likely explained by nulliparity rather than ART treatment. The increased risk of borderline ovarian tumors after ART must be interpreted with caution because no dose-response relationship was observed.