Login / Signup

SB431542 partially inhibits high glucose-induced EMT by restoring mitochondrial homeostasis in RPE cells.

Jingjing CaoMingfei JiaoZhenyu KouFeifei HanLijie Dong
Published in: Cell communication and signaling : CCS (2024)
SB431542 improved EMT in RPE cells by maintaining mitochondrial homeostasis via the ERK1/2 and GSK3β/β-catenin pathways. Video Abstract SB431542 inhibits EMT in RPE cells under high glucose conditions.
Keyphrases
  • high glucose
  • induced apoptosis
  • endothelial cells
  • epithelial mesenchymal transition
  • cell cycle arrest
  • signaling pathway
  • oxidative stress
  • pi k akt
  • cell proliferation
  • cell death