Role of Nitric Oxide in the Antipruritic Effect of WIN 55,212-2, a Cannabinoid Agonist.
Oyku Zeynep GercekBusra OflazNeslihan OguzKoray DemirciOzgur GunduzAhmet UlugolPublished in: Basic and clinical neuroscience (2020)
Our findings indicate that exogenous cannabinoids may attenuate serotonininduced scratches and NO does not mediate the antipruritic effect of WIN 55,212-2. On the other hand, neuronal NOS inhibition may play a role in the production of serotonin-induced scratches.