Phytochemical Analysis and Toxicity Study of Aristolochia paucinervis Rhizomes Decoction Used in Moroccan Alternative Medicine: Histopathological and Biochemical Profiles.
Mohammed BourhiaAyoub LahmadiHafid AchtakAyoub TouisJamal ElbrahmiRiaz UllahAbdelaaty A ShahatHafiz Majid MahmoodSouad AboudkhilLaila BenbacerNaima KhlilPublished in: Evidence-based complementary and alternative medicine : eCAM (2019)
RDA showed toxicity in mice at a dose of 1 g/kg/day under subacute toxicity conditions. RDA is safe at a single dose inferior to 4 g/kg of body weight. The plant extract prepared by decoction showed more poisonous effect than the extract prepared by maceration at room temperature.