Simultaneous determination of gastric cancer biomarkers pepsinogen PGI/PGII using element tagged immunoassay coupled with inductively coupled plasma mass spectrometry detection.
Wencan JiangGongwei SunYuqing ZhangZhian HuXinyu WenShasha MenZhi XingSichun ZhangBiao HuangChengbin WangPublished in: Journal of clinical laboratory analysis (2020)
We established a mass spectrometry-based immunoassay for the simultaneous detection of PGI and PGII in a single analysis. The element tagged immunoassay coupled with ICP-MS detection has high sensitivity, accuracy, and specificity in clinical serum sample analysis.
Keyphrases
- mass spectrometry
- label free
- simultaneous determination
- liquid chromatography
- high performance liquid chromatography
- loop mediated isothermal amplification
- sensitive detection
- tandem mass spectrometry
- capillary electrophoresis
- high resolution
- multiple sclerosis
- gas chromatography
- ms ms
- high resolution mass spectrometry
- quantum dots