Species-level, metagenomic and proteomic analysis of microbe-immune interactions in severe asthma.

Maisha F Jabeen Nicholas S R Sanderson Mariaenrica Tinè Gillian Donachie Clair Barber Adnan Azim Laurie C K Lau Thomas P Brown Ian Douglas Pavord Anoop J Chauhan Paul Klenerman Teresa L Street Emanuele Marchi Peter J Howarth Timothy Stopford Christopher Hinks

Published in: Allergy (2024)

This species-level integrated analysis reveals central, but distinct associations between potentially pathogenic bacteria and airways inflammation in severe asthma.

Keyphrases

oxidative stress
cystic fibrosis
genetic diversity