Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner.

Dan HuangShuang ShenQian ZhuangXin YeYueqin QianZhixia DongXin Jian Wan

Published in: Chinese medicine (2024)

Taken together, GLP ameliorates CG formation by regulating cholesterol and BA metabolism in an FXR-dependent manner. Our study demonstrates that GLP may be a potential strategy for the prevention against CG disease.

Keyphrases

low density lipoprotein
mouse model
human health
risk assessment
climate change