Monocyte/macrophage mediates the impact of depression on Crohn's disease.

Xin ZhangPengbo WangYi YangXin GaoYu TangYing LuoXiangbing DengYongyang YuLanlan ZhangYan Zhang

Published in: Scandinavian journal of gastroenterology (2023)

Monocyte/macrophage may underlie the impact of depression upon CD via decreased phagocytosis, increased pro-inflammatory cytokine production, inducing CD4 + T cell differentiation toward Th1/Th17 cells rather than Treg cell, and impairing macrophage-enhanced epithelial barrier.

Keyphrases

adipose tissue
dendritic cells
depressive symptoms
induced apoptosis
sleep quality
endothelial cells
single cell
peripheral blood
cell cycle arrest
cell therapy
nk cells
oxidative stress
cell death
endoplasmic reticulum stress
bone marrow