Glycocalyx Disruption Triggers Human Monocyte Activation in Acute Heart Failure Syndromes.
Olga G GrushkoSteven ChoAshley M TateRobert S RosensonDavid J PinskyJacob M HausScott L HummelSascha N GoonewardenaPublished in: Cardiovascular drugs and therapy (2022)
These studies indicate that the mGAC is dynamically remodeled during monocyte activation and that mGAC remodeling itself may contribute to the heightened inflammation associated with AHF.