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ADSC-derived exosomes provide neuroprotection in sepsis-associated encephalopathy by regulating hippocampal pyroptosis.
Yunliang Zhan
Li Zhang
Jie Sun
Hao Yao
Jiu Chen
Mi Tian
Published in:
Experimental neurology (2024)
ADSC-derived exosomes confer neuroprotection in SAE models by mediating the NLRP3/caspase-1/GSDMD pathway, thereby ameliorating cognitive impairment.
Keyphrases
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cerebral ischemia
cognitive impairment
mesenchymal stem cells
stem cells
brain injury
nlrp inflammasome
cell death
intensive care unit
early onset
induced apoptosis